Prasanna LAB
Finding Cure for Heart Diseases


PrasannaLAB members

Prasanna Laboratory
Overall research theme in Prasanna's laboratory is to understand the mechanisms of cardiovascular diseases that will aid in developing innovative new therapies and translate that information to the clinics to treat heart disease and improve lives of patients. Learn more about our research.
Lab News

Two-year American Heart Association Postdoctoral fellowship awarded to the lab (congrats D.J!).
for his research proposal that will study role of Serine Threonine Kinases in endothelial progenitor cells (EPC) under diabetic conditions.
                                                                  .................................................................

Manuscript accepted for publication in Scientific Reports (congratulations S.S.B!).
The work demonstrates that miR-126 overexpression rescues diabetes-induced impairment in macrophage clearance of dead cardiomyocytes. Learn more
                                                                  .................................................................

Manuscript accepted for publication in Biochem Biophys Res Commun. (Congratulations P.J!).
The work demonstrates that miR-9 inhibits hyperglycemia-induced pyroptosis in human ventricular cardiomyocytes. Learn more
                                                                  .................................................................

HMRI President’s Award for Transformational Excellence-Peer Reviewed Publication (Congratulations to the team!).
The award was given to the team for publication in J Am Coll Cardiol. (please see the title below).
                                                                  .................................................................

Manuscript accepted for publication in J Am Coll Cardiol. (Congratulations Darukesh!).
The manuscript is titled "Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34+ Cells Deficient in MicroRNA-377".
                                                                  .................................................................

Dr. Krishnamurthy elected a "Fellow of American Heart Association (FAHA)"
This is a distinguished award conferred by the AHA to recognize scientists for excellence, innovative and sustained contributions in the areas of scholarship, education, and volunteer service and/or leadership within the AHA/ASA.
                                                                  .................................................................

Two-year American Heart Association Postdoctoral fellowship awarded to the lab (congrats A.T.R)
for his research proposal that will study macrophage cell-based therapy for cardiac regeneration and repair under diabetic conditions (work supported through AHA funds from Jul 2015-Jun 2017).
                                                                  .................................................................

Prasanna receives AHA Grant-in-Aid award
This study will evaluate the effect of diabetes on EPC/human CD34 cell senescence and its implications on cardiovascular regeneration after injury (work supported through AHA funds from Jul 2015-Jun 2017).
                                                                  .................................................................

Prince awarded AHA-BCVS New Investigator Travel Award
He will present his research work on mRNA stability in cardiac fibrosis and dysfunction at AHA-BCVS symposium, New Orleans, USA.
                                                                  .................................................................

Manuscript accepted for publication in Experimental Dermatology (Congratulations A.T.R!).
The work demonstrates that Sirtuin-6 deficiency exacerbates diabetes-induced impairment of wound healing.
Learn more
                                                                  .................................................................

Darukeshwara receives Best Poster Award
for his work on miRNAs in human CD34 cell biology and function at George and Angelina Kostas Research Center for Cardiovascular Nanomedicine Inaugural International Meeting, Houston Methodist Research Institute, TX.
                                                                  .................................................................